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On top of that, the indole Main is substituted at R3 with a carbonyl group that's also bonded into a napthalene moeity. Napthalene is actually a bicyclic structure of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it to be a ketone. JWH-018 is surely an analog of THJ-018, wherein the core indazole framework is substituted using